Schweizer-Reneke was formerly part of the old Transvaal Republic. Founded on 1 October 1888, the town is situated on the banks of the Harts River, with six regional roads exiting the town. The town is named after Captain C.A. Schweizer and Field Cornet C.N. Reyneke. Both men distinguished themselves and were among the ten soldiers killed while storming the stronghold of the Khoekhoe Korana and their chief David Massouw on the nearby Mamusa Hill on 2 December 1885 during an action to put an end to cattle rustling in the area. The remains of the stone fortifications of Chief David Massouw can still be seen on Mamusa Hill.